Laboratory of Drug-Toxicology

Coordinator:

Eugenia Gallardo

PHONE NUMBER

+351 275 241 255

E-MAIL

egallardo@fcsaude.ubi.pt

The Laboratory of Drug-Toxicology develops its activity in the area of clinical analysis and also in the environmental field – water, food, and others of equal health interest and safeguard public health.

Research

Dosing of drugs and xenobiotics in biological matrices;
Evaluation of impurities and characterization of active principles;
Assay of active substances and contaminants in water and food;
Evaluation and characterization of plant extracts;
Evaluation of enzymatic activity in material of biotechnological origin.

Services

Determination of pesticide residues in water and food;
Determination of veterinary residues in food;
Determination of metals and metalloids in water, food and biological fluids;
Determination of resveratrol in wines;
Evaluation of impurities and characterization of active principles;
Determination of enzymatic activity in material of biotechnological origin;
Dosing of medicaments and xenobiotics in biological matrices;
Determination of antioxidant activity in plant extracts;
Determination of polyphenols in plant extracts;
In vitro toxicity studies;
Evaluation of pharmacological interactions between drugs and between drugs and plant extracts;
Toxicology consulting services.

Equipment

High resolution liquid chromatography coupled to triple quadrupole mass spectrometry (LC-MS / MS)
Gas chromatography coupled to a Triple Quadrupole mass spectrometer (GC-MS / MS)
Cromatography gas coupled to flame ionization (GC / FID);
Gas chromatography coupled mass spectrometry (GC-MS);
High resolution liquid chromatography coupled to photodiode detector (HPLC / DAD);
High resolution liquid chromatography coupled to fluorescence detector (HPLC / FLD);
Vacuum dissecting oven;
UV / VIS spectrophotometry.